Cat No.：31A040 ★Download Datasheet★
INTRODUCTION
The dsDNA-specific autoantibodies (anti-dsDNA) are considered a specific marker for systemic lupus erythematosus (SLE), due to
the high clinical associations.
The presence of anti-dsDNA autoantibodies in other pathological conditions and in healthy subjects is very rare (< 0.5%). In contrast, they may be present in SLE patients even before they develop clinical symptoms.
Therefore, regular measurement of anti-dsDNA autoantibodies in blood is important for early diagnosis, as well as monitoring the
progression of SLE.
Assay Characteristics:
References:
1. D. A. Isenberg, et al. Fifty Years Of Anti-ds Dna Antibodies: Are We Approaching Journey's End? Rheumatology, Vol. 46, No. 7, Pp. 1052–1056,
2007.
2. G. C. Tsokos. Systemic Lupus Erythematosus. The New England Journal Of Medicine, Vol. 365, No. 22, Pp. 2110–2121, 2011.
3. E. Cozzani, et al. Serology Of Lupus Erythematosus: Correlation Between Immunopathological Features And Clinical Aspects,” Autoimmune
Diseases, Vol. 2014, Article Id 321359, 13 Pages, 2014.