Polyclonal Antibody against Human PM20D1
Size: 0.1 mg
Introduction
PM20D1 is a bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids.
These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In a UCP1-independent manner, maybe
through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. PM20D1 may
indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.
Purification
Antigen affinity-purified
Immunogen
Recombinant human PM20D1 protein (Cat. No.: 41700) expressed in mammalian cells.
Specificity
The antibody detects human PM20D1 in western blot and sandwich ELISA. In sandwich ELISA, no cross reactivity with recombinant mouse PM20D1 is observed.
Formulation
Liquid in phosphate-buffered saline (PBS).
Storage
Store at –20°C for less than one week. For long-term storage, aliquot and freeze at -80°C. Avoid repeated freeze/defrost cycles.
Application/Usage
Western blot - This antibody can be used in western blot analysis with appropriate secondary antibody to detect human PM20D1.
ELISA - This antibody can be used as capture antibody in Human PM20D1 ELISA (Cat. No.: 31700).